The Africa Center is located at 1280 Fifth Avenue in New York City New York.  Situated at the intersection of 110th and Fifth Avenues, it is one of the many cultural institutions on Museum Mile. 

Its designation to be developed in Harlem, a community noted for its significant Black population and stature in Black culture, was completely purposeful.  Developed by Caples Jefferson Architects, the design and décor of The Africa Center honor the diverse stylings created and influences by those indigenous to the massive continent and the Africa Diaspora.