Set in 1962 Eve’s Bayou is centered upon the life of ten-year-old Eve Batiste (Jurnee Smollett) and her family in Louisiana. The child of an affluent, Creole American family, Eve’s parents are Louis Batiste (Samuel L. Jackson), a physician, and Roz (Lynn Whitfield), a socialite; her siblings are Cisely (Meagan Good), her older sister, and Poe (Smollett’s real-life brother, Jake Smollett), her younger brother.
Rounding out the family is Mozelle Batiste Delacroix (Debbi Morgan), the sister of Louis; widowed three times, she has the ability to be psychic and see the future of others but not her own. Part of the affluence of the Batiste family stems from their ancestral ties to the wealthy French founder of their community. His life was saved by an enslaved African woman, also named Eve, and for her act, she and her sixteen children were given their freedom.
The events in this film occur primarily during the span of one summer. Eve lives a very privileged life and is dearly loved by her, seemingly, perfect family. However, when she accidently observes her father being intimate with another woman, Mrs. Matty Mereaux, (Lisa Nicole Carson), Eve is devastated. Mereaux is a friend of her family and married to Lenny Mereaux (Roger Gueneuver Smith), a local schoolteacher. When she confides to her sister what she saw, Cisely attempts to convince Eve differently.